Journal of South China University of Technology (Natural Science Edition) ›› 2009, Vol. 37 ›› Issue (12): 18-22.

• Materials Science & Technology • Previous Articles     Next Articles

Effect of High-Amylose Corn Starch on Structure and Properties of Poly （ε-Caprolactone） Tissue Engineering Scaffolds

Wang Xue-yu  Chen Ling  Su Jian-yu  Li Xiao-xi  Yu Long   

  1. Research Institute of Light Industry and Chemical Engineering, South China University of Technology Guangzhou 510640, Guangdong, China
  • Received:2009-06-24 Revised:2009-09-16 Online:2009-12-25 Published:2009-12-25
  • Contact: 王雪毓（1983-），女，博士生，主要从事淀粉改性技术、天然高分子医学应用的研究． E-mail:xueya218@sohu.com
  • About author:王雪毓（1983-），女，博士生，主要从事淀粉改性技术、天然高分子医学应用的研究．
  • Supported by:

    广东省自然科学基金团队项目（0500617）;广东省科技攻关项目（2005A10903002）;广东省教育部产学研项目（2006D90404004）

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Abstract:

:By using high-amylose corn starch to modify poly （ε-caprolactone） （PCL）, starch/poly （ε-caprolactone） （SPCL） tissue engineering scaffolds were prepared via the solvent casting/particulate leaching. Then, the molecular chain structure, crystallinity, hydrophilicity and cell compatibility of the modified scaffolds were investigated by means of FT-IR, XRD, dynamic contact angle measurement and cell compatibility test. The results show that the addition of starch with proper dosage may decrease the crystallinity and improve the hydrophilicity and cell compatibility of the scaffolds, and that the scaffold with a starch dosage of 30% is of the best cell adhesion, proliferation and activity;, which promises to be applied to bone tissue engineering.

Key words: poly（ε-caprolactone）, high-amylose corn starch, tissue engineering scaffold, structure, property