关键词: 精细化学品, 绿色氧化, 合成, 固体催化剂, 仿生氧化

Abstract:

As oxidation is widely used in the synthesis of fine chemicals , employing green methods into oxidation processes can effectively reduce the pollution and improve the atom economy. In this paper , some catalyst systems , such as recyclable and reused solid catalysts , efficient homogeneous metalloporphyrins and metal phthalocyanines , and the metal-free cyclodextrin catalyst system , were developed by using molecular oxygen and hydrogen peroxide as the oxidants. The results show that (1) when ruthenium is used as the active center , Ru-modified ferrite spinels , Ru-modified hydrotalcite and Ru-modified HMS zeolites are all proved to be effective catalysts in the presence of molecular oxygen; (2) when non-precious metals are used as active centers , nickel and vanadium are well fabricated to be effective catalysts; (3) as to the biomimetic oxidation , metalloporphyrins with simple structure can effectively convert cyclohexane to adipic acid , alkenes to epoxides and sulfides to sulfoxides; (4) metal phthalocyanines are also effective catalysts towards nitrotoluene oxidation to para-nitro benzoic acid; and (5) as a metal-free catalyst ， β-cyclodextrin can oxidize various organic compounds in water under mild conditions. All the above-mentioned findings indicate that solid catalysts and biomimetic catalysts can activate molecular oxygen or hydrogen peroxide to furthermore achieve green oxidation under mild conditions.

Key words: fine chemical, green oxidation, synthesis, solid catalyst, biomimetic oxidation