Effect of Low-Power Millimeter Wave Radiation on Gene Expression Profile of HL60 Leukemia Cell

Journal of South China University of Technology (Natural Science Edition) ›› 2008, Vol. 36 ›› Issue (4): 133-137.

• Biology Science • Previous Articles Next Articles

Effect of Low-Power Millimeter Wave Radiation on Gene Expression Profile of HL60 Leukemia Cell

Lai Huang-wen¹ Jiang Yue-hua² Zhang Hong-bin² Lai Sheng-li¹ Wang Jie² Wu Jie²

1. School of Electronic and Information Engineering, South China University of Technology, Guangzhou 510640, Guangdong, China; 2. Center of Medical Research, General Hospital of Guangzhou Military Command, Guangzhou 510010, Guangdong, China

Received:2007-05-14 Revised:2007-11-30 Online:2008-04-25 Published:2008-04-25
Contact: 赖晃文（1956-），男，主任医师，博士生，主要从事电磁场生物效应、建模及超微病理研究． E-mail:chardlai@sina．com
About author:赖晃文（1956-），男，主任医师，博士生，主要从事电磁场生物效应、建模及超微病理研究．
Supported by:
广东省科技发展基金资助项目（2002C31101）;广东省自然科学基金资助项目（990587）

Abstract

Abstract:

In this paper, the gene chip technology was adopted to reveal the difference in gene expression profile between the HL60 leukemia cells exposed to millimeter wave （MMW） at 41.32GHz and the sham-exposed group. The gene expressions of IL-7, EGF and LGALS3 were then confirmed by means of RTR-PCR method. The results show that, after the MMW radiation for 60 min, HL60 cells proliferate and 18 up-regulated genes and 306 downregulated genes are found, and that the down-regulated genes of IL-7, EGF and LGALS3 obtained by RT-PCR method are consistent with those obtained by gene chip technology. It is thus concluded that the radiation of MMW promotes the proliferation of HL60 cells by altering the gene expression profile.

Key words: cell, millimeter wave, radiation, gene expression, oligonucleotide, gene chip

Lai Huang-wen Jiang Yue-hua Zhang Hong-bin Lai Sheng-li Wang Jie Wu Jie. Effect of Low-Power Millimeter Wave Radiation on Gene Expression Profile of HL60 Leukemia Cell[J]. Journal of South China University of Technology (Natural Science Edition), 2008, 36(4): 133-137.

[1]	LI Fang, GUO Weisen, ZHANG Ping, et al.. Prediction Technique for Remaining Useful Life of Bearing Based on Spatial-Temporal Dual Cell State [J]. Journal of South China University of Technology(Natural Science Edition), 2023, 51(9): 69-81.
[2]	ZHANG Xinggang, DAI Dan, TANG Yan . Statistical Voronoi Model for Monodisperse Disk Packings [J]. Journal of South China University of Technology(Natural Science Edition), 2023, 51(2): 122-130.
[3]	LIN Yongjie, CHEN Ning, LU Kai. Vehicle Trajectory Tracking at Intersections Based on Millimeter Wave Radar Point Cloud [J]. Journal of South China University of Technology(Natural Science Edition), 2023, 51(10): 110-125.
[4]	YE Jun, LIU Luying, HUANG Zhuosheng, et al. Study on CMC/CS/Ca²⁺ Composite Hydrogel for Transdermal Delivery of SPE in vitro and Its Antioxidant Activity [J]. Journal of South China University of Technology(Natural Science Edition), 2023, 51(1): 51-60.
[5]	HUANG Huihua, TANG Lu, LIU Yushan, et al. Preparation of Pineapple Peel Cellulose Nanocrystals and Their Environment Stability in Pickering Emulsions [J]. Journal of South China University of Technology(Natural Science Edition), 2022, 50(8): 1-11.
[6]	ZHENG Juanyi, MU Jinyu, XING Lirong, et al. Beamspace Channel Estimation Algorithm Based on Deep Compressed Sensing [J]. Journal of South China University of Technology(Natural Science Edition), 2022, 50(12): 101-108.
[7]	XIE Qiuling, TAN Chumin, WANG Yayu, et al. Proteomic Analysis of CHO-DG44 Cell Line Expressing Foreign Protein [J]. Journal of South China University of Technology(Natural Science Edition), 2022, 50(11): 74-81.
[8]	QI Weiwei, MA Siwei, ZHOU Nanjie . Construction and Application of Cellular Automaton Model of Traffic Flow in Freeway Diverging and Merging Areas [J]. Journal of South China University of Technology(Natural Science Edition), 2022, 50(10): 11-18.
[9]	HUANG Yanbo, SUN Weizheng, HOU Yi, et al. Protective Mechanism of Yeast Hydrolysates Against the Oxidative Injury on Human Umbilical Vein Endothelial Cells [J]. Journal of South China University of Technology (Natural Science Edition), 2022, 50(1): 23-29.
[10]	LUO Zhigang YANG Huan QI Liang. Study on the Properties of Rhamnolipids as Biosurfactants [J]. Journal of South China University of Technology (Natural Science Edition), 2022, 50(1): 30-37.
[11]	YE Jun YE Fang XIONG Jian. Structure and Properties of Eu3+-Containing PVA/CMC Fluorescent Hydrogels [J]. Journal of South China University of Technology (Natural Science Edition), 2021, 49(9): 37-45.
[12]	XU Xilin, ZHOU Xiaoli, ZHENG Liuqing, et al. Antioxidant Activity of Lactobacillus rhamnosus LR ZB1107-01 in Vitro [J]. Journal of South China University of Technology (Natural Science Edition), 2021, 49(3): 88-94.
[13]	BAI Xingying, JIAN Qifei, LUO Lizhong, et al. Application of Vapor Chamber in the Thermal Management of Proton Exchange Membrane Fuel Cell Stack#br# [J]. Journal of South China University of Technology (Natural Science Edition), 2021, 49(2): 25-32.
[14]	XU Jun, LI Zhefan, Zhang Yang, et al. Points Selection in High-Dimensional Ｒandom-Variate Space for Simulating Stationary Stochastic Wind Field [J]. Journal of South China University of Technology (Natural Science Edition), 2021, 49(10): 95-103.
[15]	YAO Ruohe WANG Xiaoting. A New Kind of Ring Oscillator Structure [J]. Journal of South China University of Technology (Natural Science Edition), 2020, 48(5): 67-74.

Effect of Low-Power Millimeter Wave Radiation on Gene Expression Profile of HL60 Leukemia Cell

PDF

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments