Journal of South China University of Technology (Natural Science Edition) ›› 2013, Vol. 41 ›› Issue (3): 142-146.doi: 10.3969/j.issn.1000-565X.2013.03.021

• Chemistry & Chemical Engineering • Previous Articles    

Synthesis and Anion Recognition Properties of Sulfonylurea Receptor

Qu Jin-qing1 Wan Wen1 Yong Xue1 Su Ming-jian1 Yan Yi-chen2 Liu Rui-yuan2   

  1. 1.School of Chemistry and Chemical Engineering,South China University of Technology,Guangzhou 510640,Guangdong,China;2.School of Pharmaceutical Sciences,Southern Medical University,Guangzhou 510515,Guangdong,China
  • Received:2012-08-23 Revised:2012-11-28 Online:2013-03-25 Published:2013-02-01
  • Contact: 瞿金清(1970-)，男，教授，博士生导师，主要从事精细化学品的合成与应用研究． E-mail:cejqqu@scut.edu.cn
  • About author:瞿金清(1970-)，男，教授，博士生导师，主要从事精细化学品的合成与应用研究．
  • Supported by:

    国家自然科学基金资助项目( 21074073， 51173050， 21244007)

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Abstract:

A novel sulfonylurea anion receptor,namely bis-( 4'-nitro phenyl) sulfonylurea,was synthesized andapplied to the naked-eye detection of anions by observing the color change of receptor solution after the addition ofanions,and obvious color change of the solution,namely F- -induced brown yellow or CH3CO2- -induced lightyellow,was observed.However,the color slightly changed when such other anions as NO3- ,Br- ,Cl- and HSO4- were introduced in the solution.Afterwards,the binding ability of the receptor with mono-anions was tested bymeans of UV-vis spectrophotometry titration method,with rather strong affinity of sulfonylurea to F- and CH3CO2-being revealed. Jobs plot indicates that the receptor and F- groups form a kind of complex with 1:2 stoichiometry.Moreover,the UV absorption spectra of methanol for the complex confirm that the receptor binds with anions withthe help of hydrogen bond.

Key words: sulfonylurea, receptor, anion recognition, naked-eye detection

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