紫外线对离子互补型自组装寡肽EAK16-Ⅱ聚集状态的影响

华南理工大学学报（自然科学版） ›› 2006, Vol. 34 ›› Issue (8): 51-54.

紫外线对离子互补型自组装寡肽EAK16-Ⅱ聚集状态的影响

欧阳新平¹ P．Chen²

1．华南理工大学化工与能源学院，广东广州510640；2．Dept．of Chemical Engineering，Univ．of Waterloo，200 Univ．Avenue，Waterloo，Ontario，Canada，N2L 3GI

收稿日期:2005-10-19 出版日期:2006-08-25 发布日期:2006-08-25
通信作者: 欧阳新平(1966-)，男，博士，副研究员，主要从事生物质资源研究 E-mail:ceouyang@scut.edu.cn
作者简介:欧阳新平(1966-)，男，博士，副研究员，主要从事生物质资源研究

Efect of Ultraviolet Irradiation on Aggregation M orphology of Ionic Complementary Self-Assembly Oligo-Peptide EAK16-Ⅱ

Ouyang Xin-ping¹ P．Chen²

1.School of Chemical and Energy Engineering,South China Univ.of Tech.,Guangzhou 5 10640,Guangdong,China;2.Dept.of Chemical Engineering,Univ.of Waterloo,200 Univ.Avenue,Waterloo,Ontario,Canada, N2L 3G1

Received:2005-10-19 Online:2006-08-25 Published:2006-08-25
Contact: 欧阳新平(1966-)，男，博士，副研究员，主要从事生物质资源研究 E-mail:ceouyang@scut.edu.cn
About author:欧阳新平(1966-)，男，博士，副研究员，主要从事生物质资源研究

摘要/Abstract

摘要： 借助原子力显微镜对离子互补型自组装寡肽EAK16一II在水溶液中自组装聚集形态受紫外线的影响进行了研究．研究结果表明，紫外线改变了该类寡肽在水溶液中自组装形成的纳米结构．当用波长为365nm的紫外线照射2h后，离子互补型自组装寡肽的聚集态从纤维状结构转变为球形结构．从成核模型分析，其原因是由于紫外线照射导致了自组装聚集体分子间作用力的破坏以及β片层向β转角的转变．

关键词: 自组装寡肽, 聚集状态, 紫外线, 原子力显微镜

Abstract:

The effect of ultraviolet irradiation on the serf-assembly aggregation morphology of ionic complementary self-assembly oligo-peptide EAK1 6-Ⅱin aqueous solution was studied using an atomic force microscopy.It is found that the ultraviolet iradiation changes the nanostructure formed by the self-assembly in the aqueous s0lution.and a variation from a fibrillar structure into a globular structure of the aggregation morphology can be caused after an ira diation with 365 nm ultraviolet for 2 h.According to the nuclear model.there draws a conclusion that the ab0ve mentioned change results from the destruction of the interm olecular forces of the assembled oligo-peptide as well as from the transition from β sheet into β turn.

Key words: serf-assembly oligo-peptide, aggregation morphology, ultraviolet, atomic force microscope

欧阳新平 P．Chen. 紫外线对离子互补型自组装寡肽EAK16-Ⅱ聚集状态的影响[J]. 华南理工大学学报（自然科学版）, 2006, 34(8): 51-54.

Ouyang Xin-ping P．Chen. Efect of Ultraviolet Irradiation on Aggregation M orphology of Ionic Complementary Self-Assembly Oligo-Peptide EAK16-Ⅱ[J]. Journal of South China University of Technology (Natural Science Edition), 2006, 34(8): 51-54.

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