In order to improve the transmission quality and coding eficiency of medical images,a novel bitplane lifting algorithm and an improved SPIHT(Set Partitioning in Hierarchical Trees)algorithm based on ROI(Region of Interest)shape estimation is proposed.By implementing the interlaced lifting of bitplane,the relative quality of the ROI and the background becomes adjustable without transmitting any mask information.For the bitplane after the lifting,the estimated mask inform ation can be obtained by transmitting the geometric parameter of the circum rule shape of ROI.According to the estimated mask inform ation,zero trees are determined be~rehand,so that the coding bits of the image can be saved.Experimental results show that,at the same truncation bit rate,both the ROI and the whole image obtained by the improved algorithm are of better image quality than those obtained by the traditional SPIHT algorithm,and that the lower the bit rate is,the more obvious the results are.