A novel sulfonylurea anion receptor,namely bis-( 4'-nitro phenyl) sulfonylurea,was synthesized andapplied to the naked-eye detection of anions by observing the color change of receptor solution after the addition ofanions,and obvious color change of the solution,namely F^- -induced brown yellow or CH₃CO₂^- -induced lightyellow,was observed.However,the color slightly changed when such other anions as NO₃^- ,Br^- ,Cl^- and HSO₄^- were introduced in the solution.Afterwards,the binding ability of the receptor with mono-anions was tested bymeans of UV-vis spectrophotometry titration method,with rather strong affinity of sulfonylurea to F^- and CH₃CO₂^-being revealed. Jobs plot indicates that the receptor and F^- groups form a kind of complex with 1:2 stoichiometry.Moreover,the UV absorption spectra of methanol for the complex confirm that the receptor binds with anions withthe help of hydrogen bond.