Journal of South China University of Technology(Natural Science Edition) ›› 2007, Vol. 35 ›› Issue (6): 106-110.

• Chemistry & Chemical Engineering • Previous Articles     Next Articles

Preparation and Characterization of Liposoluble Chlorogenic Laurate

Xiang Zhi-nαn1  Zhan Yu2  Ning Zheng-xiang1   

  1. 1. School of Light Industry and Food Sciences , South China Univ. of Tech. , Guangzhou 510640 , Guangdong , China;2. School of Chemistry and Chemical Engineering , Guangzhou Univ. , Guangzhou 510091 , Guangdong , China
  • Online:2007-06-25 Published:2007-06-25
  • Contact: 向智男(1982-)，女，博士生，主要从事食品化学研究。 E-mail:xiangwanzi2003@163. com
  • About author:向智男(1982-)，女，博士生，主要从事食品化学研究。
  • Supported by:

    广东省科技计划项目( 2005 A20303002) ;广州市科技局项目(2006J1 -C0251 )

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Abstract:

Chlorogenic acid (CGA) , a kind of natural antioxidant , has been widely applied to the fields of food , medicine and daily chemical industry. However , its application is restricted by its good water-solubility and weak liposolubility. In this research , liposoluble chlorogenic laurate (CGL) was synthesized by the acylation with lauroyl chloride (LC) in the existence of alkali catalyst in non-water phase , and yellowish CGL powders with a yield of 81. 24% were obtained under the optimal synthesis conditions determined via single-factor tests and orthogonal experiments , that is , carrying out the acylation at 35  ℃ for 8 h with a nCGA : nLC : nTEA ratio of 1: 1: 1. 5 and with dimethylformamide as the solvating agent and the thinner. Then , the structure of CGL was characterized by means of UV -Vis , IR , ESI-MS , 1 HNMR and element analytical method. The feasibility and rationality of the molecule modification for CGA were finally demonstrated by the method of quantum chemistry calculation.

Key words: chlorogenic acid, chlorogenic laurate, liposolubility, characterization