Journal of South China University of Technology (Natural Science Edition) ›› 2006, Vol. 34 ›› Issue (12): 30-34.

• Biological Engineering • Previous Articles     Next Articles

Enantioselectivity of Candida rugosa Lipase-Catalyzed Interesterification of(R,S)-2-Octano

Shi Xian-ai1  Lou Wen-yong1  Zong Min-hua1  Guo Yang-hao2  Meng Chun2   

  1. 1.School of Biological Science and Engineering,South China Univ.of Tech.,Guangzhou 510640,Guongdong,China;2.College of Biological Science and Tech.,Fuzhou Univ.,Fuzhou 350002,Fujian,China
  • Received:2005-07-12 Online:2006-12-25 Published:2006-12-25
  • Contact: 宗敏华, 教授, 博士生导师. E-mail: btmhzong@scut. edu. cn E-mail:shixa@ fzu. edu. cn
  • About author:石贤爱(1971- ), 男, 博士生, 主要从事生物催化方面的研究.
  • Supported by:

    福建省教育厅科技三项基金资助项目( JB04028

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Abstract:

The enantioselectivity of Candida ru．gosa lipase(CRL)-catalyzed asymmetric interesterification of(R,S)-2-octanol respectively in organic solvent,reverse micelle or ionic liquid was investigated.The results indicate significant influences of reaction medium and acyl donor on the enantioselectivity of CRL.In toluene,the enantio-selective rate E for CRL-catalyzed interesterification of(R,S)-2-octanol wi山ethyl chloroacetate is faifly hiSh(E=92.2).In reverse micelle CTAB/butanol/isooctane/H2O,CRL displays rather high enantioselective rate(E»100)when vinyl acetate is used as the acyl donor.However,in ionic liquid [ bmim ] PF6,CRL shows little enantio-selectivity．

Key words: Candida rugosa lipase, 2-octanol, interesterification, enantioselectivity, reaction medium