华南理工大学学报(自然科学版) ›› 2004, Vol. 32 ›› Issue (2): 80-84.

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外界刺激与神经细胞电位发放的关系

刘深泉 关毅璋   

  1. 华南理工大学 应用数学系‚广东 广州510640
  • 收稿日期:2003-01-13 出版日期:2004-02-20 发布日期:2015-09-07
  • 通信作者: 刘深泉(1964-)‚男‚副教授‚主要从事应用数学和生物力学的研究. E-mail:mashqliu@scut.edu.cn
  • 作者简介:刘深泉(1964-)‚男‚副教授‚主要从事应用数学和生物力学的研究.
  • 基金资助:
    国家自然科学基金资助项目(19902005)

Relationship Between External Stimulus and the Potential Spike of the Neural Cell

Liu Shen-quan Guan Yi-zhang   

  1. Dept.of Applied Mathematics‚South China Univ.of Tech.‚Guangzhou510640‚Guangdong‚China
  • Received:2003-01-13 Online:2004-02-20 Published:2015-09-07
  • Contact: 刘深泉(1964-)‚男‚副教授‚主要从事应用数学和生物力学的研究. E-mail:mashqliu@scut.edu.cn
  • About author:刘深泉(1964-)‚男‚副教授‚主要从事应用数学和生物力学的研究.

摘要:  利用数值方法和神经细胞膜电位的 Hodgkin-Huxley 方程‚研究了直、交流电和噪声刺激对神经细胞膜电位发放的影响.通过分析刺激后神经细胞膜电位发放的振幅、频率和峰间距离等特征‚得到了外界直流电流刺激的强度与刺激后膜电位发放振幅的递减关系.交流电流刺激的强度和振幅对应出现复杂的振幅窗口和频率窗口;Gauss 噪声的影响随刺激强度的增加可破坏电位发放的节律.

关键词: 神经细胞, 动作电位, 发放, 噪声刺激

Abstract: With the help of numerical method and the Hodgkin-Huxley equation of neural cell membrane potential‚the effect of external stimulus such as direct current‚alternating current and noise on the potential spike of neural cell membrane was investigated.By analyzing the amplitude‚frequency and twonear -spike distance of potential spike after the stimulus‚a decreasing relation between the intensity of external direct -current stimulus and the amplitude of stimulated potential spike was found.Complicated
amplitude windows and frequency windows were observed corresponding to the intensity and amplitude of alternating current stimulus.With the increase of stimulus intensity‚the Gauss white noise can destroy the rhythm of potential spike.

Key words: neural cell, action potential, spike.

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