Macerated extraction is an important step of producing reconstituted tobacco sheets by paper- makingtechnology,and the extracting solution is also a major ingredient for making high- quality reconstituted tobacco coa-tings.In this paper,the main chemical components in abandoned tobacco stems and leave powders were extractedby combining an orthogonal test with single- factor experiments,with water as the solvent.Then,the effects ofmaceration time,maceration temperature and solid/liquid ratio on extraction rate were investigated,and the optimalmacerated extraction conditions for abandoned tobacco stems and leave powder were determined.The results showthat,under the optimal conditions for abandoned tobacco stems,i.e.,a maceration time of 100 min,a macerationtemperature of 60℃ and a solid/liquid ratio of 1∶ 7,the dissolution rates of water- soluble sugars and total alkaloidare 50.60% and 52.46%,respectively; and that the dissolution rates respectively reaches 73.06% and 64.57%under the optimal conditions for abandoned tobacco leave powders,that is,a maceration time of 60 min,a macera-tion temperature of 70℃ and a solid/liquid ratio of 1∶ 10.