In this paper,the background of start publication of Journal of South China University of Technology ( Natural Science Edition) is introduced,and the development history of the journal,including such four stages as the initial establishment stage,the adjustment stage,the normalization stage and the fast development stage,is reviewed. Afterwards,by summarizing the ideas and experiences of publication during the past 50 years,the authors point out that a further development direction of the journal should be explored in the aspects of thinking innovation,team construction,internal management improvement,internationalization-degree promotion and digital-publication practice participation.