Journal of South China University of Technology (Natural Science Edition) ›› 2009, Vol. 37 ›› Issue (12): 100-104.

• Biological Engineering • Previous Articles     Next Articles

Hemodynamic Effects of a New Cardiopulmonary Resuscitation： Study with Computer Model

Zhang Yan-ru1  Wu Xiao-ming2  Yuan Heng-xin3  Xu Lin1   

  1. 1. School of Computer Science and Engineering, South China University of Technology, Guangzhou 510006, Guangdong, China; 2. School of Biological Science and Engineering, South China University of Technology, Guangzhou 510006, Guangdong, China; 3. Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, Guangdong, China
  • Received:2008-10-17 Revised:2009-03-03 Online:2009-12-25 Published:2009-12-25
  • Contact: 张燕儒（1982-），女，博士生，主要从事计算机应用技术、血液循环系统建模研究． E-mail:yanruzhang2007@gmail．com
  • About author:张燕儒（1982-），女，博士生，主要从事计算机应用技术、血液循环系统建模研究．
  • Supported by:

    国家自然科学基金资助项目（30670538）;广东自然科学基金资助项目（04020048）

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Abstract:

In order to digitalize a new cardiopulmonary resuscitation （CPR） called active compression-decompression CPR with enhanced external counterpulsation and inspiratory impedance threshold valve （AEI-CPR） , the hemodynamics of human body in the conditions of normal circulation, cardiac arrest and CPR were respectively simulated with computer model, and several CPR techniques, such as the standard CPR （S-CPR） , the active compres- sion-decompression CPR （ACD-CPR） , the standard CPR with enhanced external counterpulsation （SE-CPR） , and the AEI-CPR, were compared via simulation. The results indicate that （1） S-CPR generates a forward flow （FF） of 1.1 L/rain and a coronary perfusion pressure （CPP） of 30.2 mmHg, while those generated by ACD-CPR, SE- CPR and AEI-CPR are respectively 1.2 L/rain and 31.3 mmHg, 5.2 L/rain and 57.4 mmHg, and 5.6 L/rain and 57.6 mmHg ; （2） both the SE-CPR and the AEI-CPR greatly improve the forward flow ; and （3） AEI-CPR is of the best hemodynamic effect.

Key words: cardiopulmonary resuscitation, mathematical model, enhanced external counterpulsation, forward flow, coronary perfusion pressure