In order to improve the software architecture perspective of cross-layer design, a cross-layer interaction management algorithm considering the modularization of network protocol stack is proposed and is marked as CLIM. In this algorithm, DSA and message queue mechanisms are both employed to manage cross-layer interactions, thus implementing cross-layer interactions more flexibly and maintaining the good architecture of network protocol stack. Simulated results show that CLIM helps to reduce the time cost to running cross-layer interactions, and that, by combining with IEEE 802.16 signaling mechanism, CLIM makes it possible to use multiple cross-layer designs in an 802.16 terminal.