As there have been multiple bridge collapses caused by ship impacts in China, it is important to rationally evaluate the horizontal resistance of foundations of highway bridges to ship impacts. In order to meet the require- ments of impact resistance design and evaluation, this paper proposes a nonlinear FEM-based evaluation method of the horizontal resistanee of deepwater high-pile foundations under ship impacts. Then, by analyzing the ship impact on a bridge of G325 national highway, the proposed evaluation method is compared with the calculation method presented in the national design standard. The results indicate that the proposed method is applicable to the antiimpact design of deepwater high-pile foundations of highway bridges.